Description
Receptor for the CX3C chemokine fractalkine (CX3CL1); binds to CX3CL1 and mediates both its adhesive and migratory functions (PubMed: 9390561, PubMed: 23125415). Acts as coreceptor with CD4 for HIV-1 virus envelope protein (in vitro) (PubMed: 9726990). Isoform 2 and isoform 3 seem to be more potent HIV-1 coreceptors than isoform 1 (PubMed: 14607932)